IACUC Protocol and Related Forms

Protocols must be submitted at least four (4) weeks prior to a scheduled meeting. Submit the protocol either electronically to the IACUC Administrator or deliver signed protocol to Administrative Services, Room 210. Animal Care and Use Protocol

Attachment 1 - Explanation for USDA Classification E

Attachment 2 - Use of Potentially Hazardous Agents in Animals

Protocols can initially be approved for one year with up to two one-year renewals if a Continuing Review Report is filed and approved. After three years or when the project is complete, whichever comes first, a Final Report is to be filed with the IACUC. Continuing Review/Final Report

MINOR changes to an approved IACUC protocol can be requested using the Change In Protocol form. SIGNIFICANT changes require the submission of a new protocol. Final determination of whether a minor or significant change will be made by the IACUC.

MINOR changes to existing protocols may include but are not limited to:

  • Addition of co-PI(s) or other investigators
  • Minor change in the duration, frequency or number of procedures performed on an animal
  • Addition of minor surgery or procedure
  • Need to repeat an approved experiment
  • Increase of ≤ 10% in the number of animals needed in a particular experiment
  • Addition of a different strain or gender of an approved animal species
  • Change in animal housing (but still within standard methods)
  • Substitution of qualified students/technicians or addition of investigative collaboration (does not include changes in PI)

SIGNIFICANT changes to existing protocols may include but are not limited to:

  • Change in Principal Investigator (PI)
  • Change in study objectives
  • Significant change in the duration, frequency or number of procedures performed on an animal
  • Increase in the degree of invasiveness of a procedure or discomfort to an animal
  • Change from non-survival to survival surgery
  • Increase in animal numbers >10%
  • Change or addition of species
  • Change in anesthetics or analgesics
  • Change in method or agent of euthanasia
  • Change in criteria for humane end-point
  • Change in animal housing, care and/or feeding to non-standard method
  • Addition of hazardous chemical or biological agents