Laboratory for Reproduction Research and Endocrine Analyses
Professor in Charge: Dr. Oladele Gazal
Research conducted by my laboratory focuses primarily on the regulation of gonadotropin-releasing hormone (GnRH). Our emphasis has been on the determination of how various factors, for example undernutrition, affect the hypothalamic - pituitary - gonadal axis in the rat model. Current studies in the laboratory fall into one of the following:
Evaluation of the potential role of motilin, a gut-derived peptide, as a regulator of GnRH secretion.
Immobilization stress, glutamate signaling and GnRH secretion.
Effect of sewage effluent on the secretion of GnRH and luteinizing hormone secretion (in collaboration with Dr. Schoenfuss)
Gender and age effects on glutamatergic stimulation of GnRH secretion.
Feed restriction and re-feeding effects in goats (in collaboration with scientists at Fort Valley State University, Georgia)
In addition to these studies, we run peptide and steroid hormone assays for other investigators. Several times during the year, many experiments involving undergraduate students are undertaken. Current studies include auto heat - induced hyperthermia and endocrine correlates of competition - induced stress. Through participation in the Scientific Discovery Program (SDP) and the Advanced Program in Technology and Science (APTS) of the University, the laboratory introduces high school students and those from under-represented groups to biological sciences.